How does Epilim affect pregnancy?

The use of Sodium valproate (Epilim) is contraindicated in pregnancy due to the risk to the unborn baby (fetus). Congenital malformations have been estimated to affect between 6.7%1 and 12.4%2 of children exposed to Epilim in the womb. The rate of malformations in the general population is 2-3%.

How does sodium valproate affect pregnancy?

When sodium valproate is taken during pregnancy, it can affect how the baby develops in the womb and cause ‘birth defects’, including: ‘minor malformations’ (such as small fingers and toes) and. ‘major malformations’ (such as spina bifida or a cleft palate, which may need surgery to correct them)

Can Epilim cause birth defects?

Taking sodium valproate (Epilim) in pregnancy has a high risk of birth defects and developmental problems for the baby. For this reason the indication for use in bipolar disorder has changed.

Can Epilim cause miscarriage?

Can taking sodium valproate in pregnancy cause miscarriage? One small study has shown that women who took daily sodium valproate doses of 750mg or more were about three times more likely to have a miscarriage than women not receiving epilepsy treatments during pregnancy.

Can you get pregnant on epilepsy medication?

If you’re taking anti-epileptic drugs (AEDs) and you’re planning to get pregnant, you should continue to use contraception and take your medicine until you discuss your plans with a GP or epilepsy specialist (neurologist).

Can epilepsy patient get pregnant?

A 2018 study found that overall, women with epilepsy who have no history of infertility are just as likely to get pregnant as women without epilepsy. If your seizures are not under control, that may affect your fertility, as well.

Is valproate safe in pregnancy?

Sodium valproate (Epilim) is contraindicated in pregnancy. Sodium valproate should not be used in women of child bearing potential unless other treatments are ineffective or not tolerated. The risk of congenital malformations in infants exposed to sodium valproate in utero has been estimated between 6 and 12%.

Is carbamazepine safe in pregnancy?

Answer: Similar to valproic acid, carbamazepine increases the risk of neural tube defects; however, it does not increase the risk of other malformations. Carbamazepine is also not associated with an increased risk of developmental delay.

Can I have a baby if I have epilepsy?

Fortunately, most women with epilepsy give birth to normal, healthy babies. If you take precautions, your chance of having a healthy child is greater than 90%. There are increased risks. But working closely with your doctor can help minimize those risks.

Can epilepsy be detected before birth?

There have been some reports on the prenatal diagnosis of seizure-like fetal movement detected by real time ultrasonography or by the pregnant mother (2, 3). In most of these cases, the seizure activity presented as obvious, rapid myoclonic jerking of the fetal extremities (2, 3).

Can you get pregnant while taking seizure medication?

2. Myth: It’s hard to get pregnant if you have epilepsy. Fact: Nope! Until recently, studies suggested that women with epilepsy may have fertility problems.

What are the side effects of Epilim 10 mg?

Side effects of Epilim. 1 Nausea or vomiting; 2 Bleeding, tender or enlarged gums; 3 Abdominal cramps or pain; 4 Changes in appetite; 5 Changes in your weight; 6 Irregular menstrual periods; 7 Diarrhoea; 8 Headache; 9 Unusual movements, including tremor and shaking. 10 Rapid uncontrollable movements of the eye;

What are the risks of taking Epilim while pregnant?

Also, children born to mothers who take Epilim throughout their pregnancy may be at risk of impaired cognitive development or withdrawal syndrome. However, do not stop taking Epilim unless your doctor says so as there are risks to the mother and child from uncontrolled epilepsy or uncontrolled mania episodes.

What are the side effects of Epilim (duloxetine)?

Neurological side effects of Epilim include: nervousness depression drowsiness abnormal dreams agitation ringing in the ears dry eyes tingling in the extremities

Is sodium valproate (Epilim) safe during pregnancy?

The use of Sodium valproate (Epilim) is contraindicated in pregnancy due to the risk to the unborn baby (fetus).